| Gene Symbol | OGDHPROTEIN |
| Protein Type | Enzyme |
| Function | is a multienzyme complex consisting of three subunits: OGDH (E1α), DLST (E2), and DLD (E3). |
| Molecular Weight | 116 kDa |
| GeneCards | OGDHPROTEIN |
| Human Protein Atlas | OGDHPROTEIN |
| Citric Acid Cycle | The metabolic pathway in which OGDH serves as a rate-limiting enzyme |
| Mitochondrial Dysfunction | A common feature of neurodegenerative diseases involving OGDH impairment |
| NAD+ Metabolism | Critical cofactor pathway increasingly targeted therapeutically |
| Oxidative Stress | Primary mechanism of OGDH inactivation in neurodegeneration |
| Associated Diseases | neurodegeneration |
| Interactions | DNA, GBA, LRRK2, MITOCHONDRIAL DYSFUNCTION, MTORC1, OGDHL |
| KG Connections | 42 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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