gene

OGDHL

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OGDHL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

18Outgoing

1Incoming

0Experiments

0Debates

Summary

OGDHL is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, inhibits. Associated with Cancer, Carcinoma, Hepatocellular Carcinoma. Connected to 22 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	OGDHL
Full Name	Oxoglutarate Dehydrogenase Like
Chromosome	10p14
Function	OGDHL exhibits several key functions
Primary Expression	Brain (High), Heart, Liver, Kidney
Pathways	Lipid Metabolism
UniProt ID	Q9ULX5
NCBI Gene ID	55768
Ensembl ID	ENSG00000092967
GeneCards	OGDHL
Human Protein Atlas	OGDHL
Associated Diseases	prognosis
Interactions	DNA, MITOCHONDRIAL DYSFUNCTION, MTORC1, OGDH, PDHB
KG Connections	19 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: OGDHL — AlphaFold Q9ULX5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

OGDHL — Oxoglutarate Dehydrogenase Like

gene · 523 words

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Pathway Diagram

graph TD
    OGDHL["OGDHL"]
    OGDH["OGDH"]
    OGDHL -->|"interacts with"| OGDH
    mitochondrial_dysfunction["mitochondrial dysfunction"]
    OGDHL -->|"contributes to"| mitochondrial_dysfunction
    SNCA["SNCA"]
    OGDHL -->|"upregulates"| SNCA
    prognosis["prognosis"]
    OGDHL -->|"associated with"| prognosis
    PDHB["PDHB"]
    OGDHL -->|"interacts with"| PDHB
    glucose_metabolism["glucose metabolism"]
    OGDHL -->|"regulates"| glucose_metabolism
    neurodegeneration["neurodegeneration"]
    OGDHL -->|"implicated in"| neurodegeneration
    miR_1343_3p["miR-1343-3p"]
    miR_1343_3p -->|"regulates"| OGDHL
    REST["REST"]
    REST -->|"regulates"| OGDHL
    style OGDHL fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (18)

Target	Relation	Type	Str
OGDH	interacts_with	gene	0.90
prognosis	associated_with	phenotype	0.80
PDHB	interacts_with	gene	0.80
glucose metabolism	regulates	biological_process	0.80
SNCA	upregulates	gene	0.80
Tumor	inhibits	disease	0.65
Hepatocellular Carcinoma	activates	disease	0.65
Cancer	therapeutic_target	disease	0.65
Liver Cancer	therapeutic_target	disease	0.65
Carcinoma	activates	disease	0.65
Lipid Metabolism	regulates	pathway	0.60
OGDH	inhibits	gene	0.60
MTORC1	activates	gene	0.60
CANCER	therapeutic_target	gene	0.60
MITOCHONDRIAL DYSFUNCTION	inhibits	gene	0.60
DNA	activates	gene	0.60
Mtor	activates	pathway	0.60
Mitochondrial Function	inhibits	pathway	0.60

Incoming (1)

Source	Relation	Type	Str
miR-1343-3p	regulates	gene	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning OGDHL in their description or question text

No additional research found