protein 1,208 words KG: NLRP7PROTEIN
Contents

NLRP7 Protein — NLR Family Pyrin Domain Containing 7

🔬 Protein Info
Gene SymbolNLRP7
Full NameNLR Family Pyrin Domain Containing 7
AliasesNOD27, CLR19.9
Chromosome19q13.42
Protein TypeReceptor
Functionis a member of the NOD-like receptor (NLR) family of proteins that plays complex roles in innate immunity, inflammation, and cellular homeostasis.
Subcellular Localizationand interactions
Amino Acids956 aa
Exons10
PathwaysInflammasome, Innate Immunity, pyroptosis
UniProt IDQ8WX94
NCBI Gene ID199713
Ensembl IDENSG00000124313
GeneCardsNLRP7
Human Protein AtlasNLRP7
Associated DiseasesAutoimmune
InteractionsAIM2, AND, CARD8, Caspase, Cytokine, CYTOKINES
KG Connections47 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (12)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77

Related Analyses (9)

APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 3 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 3 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)