protein 1,671 words KG: NEFLPROTEIN
Contents

Neurofilament Light Chain Protein

🔬 Protein Info
Gene SymbolNEFLPROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization| Neuronal axon (cytoskeleton) |- \! Protein Family | Type IV intermediate filam
Amino Acids543 aa
GeneCardsNEFLPROTEIN
Human Protein AtlasNEFLPROTEIN
Associated DiseasesAlzheimers_disease
InteractionsALS, AMYOTROPHIC LATERAL SCLEROSIS, BCL2, BNIP3L, C9ORF72, CNR1
SciDEX HypothesesPlasma NfL Elevation Secondary to BBB-Associated T
Plasma NfL Elevation Secondary to BBB-Associated T
KG Connections197 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (71)

VCP-Mediated Autophagy Enhancement
Score: 0.59
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
Lysosomal Membrane Repair Enhancement
Score: 0.54
Cryptic Exon Silencing Restoration
Score: 0.53
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
Vocal Cord Neuroplasticity Stimulation
Score: 0.52
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
← Prevpg 4/4

Related Analyses (24)

Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (17)

ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40
Why Does Amyloid Removal Only Slow Decline 27%? — Mechanisti
clinical · proposed · Score: 0.40
Anti-Tau Immunotherapy Dosing Optimization
clinical · proposed · Score: 0.40
Axonal Transport Dysfunction Validation in Parkinson's Disea
clinical · proposed · Score: 0.40
Blood-Based Biomarker Panel for Early AD Detection
clinical · proposed · Score: 0.40

See Also (15)

China Neurodegeneration Epidemiology
disease · Pages share 68 hypotheses
Beta-Propeller Protein-Associated Neurodegeneration (BP
disease · Pages share 68 hypotheses
Cell-Free DNA Biomarkers in Neurodegeneration
biomarker · Pages share 68 hypotheses
Swedish BioFINDER 2 Study: Biomarkers and Neurodegenera
clinical · Pages share 68 hypotheses
Olfactory Mucosa, Blood and Urine for Identification of
clinical · Pages share 68 hypotheses

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