| Gene Symbol | NAGLU |
| Full Name | Alpha-N-Acetylglucosaminidase |
| Aliases | NAGLUPROTEIN |
| Protein Type | Enzyme |
| Function | NAGLU encodes alpha-N-acetylglucosaminidase, a lysosomal enzyme that catalyzes the N-acetylglucosaminide hydrolysis in heparan sulfate glycosaminoglycans. |
| Subcellular Localization | </strong></td><td>Lysosome</td></tr> |
| Molecular Weight | 73.9 kDa |
| Amino Acids | 739 aa |
| Ensembl ID | ENSG00000108784 |
| GeneCards | NAGLU |
| Human Protein Atlas | NAGLU |
| N-linked glycosylation | Multiple sites for N-glycosylation in the N-terminal region |
| Phosphorylation | Serine and threonine phosphorylation sites |
| Proteolytic processing | Cleavage to produce mature enzyme form |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | ACTB, ATG12, ATG5, ATG7, BECN1, CTSD |
| KG Connections | 20 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!