| Gene Symbol | MYO5A |
| Full Name | Myosin Va |
| Aliases | MYO5APROTEIN |
| Chromosome | 15q21.2. |
| Function | encodes an unconventional myosin motor protein that moves towards the plus end of actin filaments. |
| Primary Expression | a tissue-specific manner, with highest levels in brain, melanocytes, and platelets |
| Molecular Weight | 205 kDa |
| Amino Acids | 855 aa |
| Ensembl ID | ENSG00000128594 |
| GeneCards | MYO5A |
| Human Protein Atlas | MYO5A |
| Two motor domains (heads) | Each motor domain contains the actin-binding site and ATPase activity required for movement |
| A lever arm | A long alpha-helical region that amplifies small conformational changes into the 36-nm step size characteristic of myosin V |
| A coiled-coil region | Mediates dimerization of the two heavy chains |
| A cargo-binding tail domain | Interacts with adaptor proteins that link myosin to specific cargoes |
| Associated Diseases | neurodegeneration |
| Interactions | CDKN2A, DNA, KIF5B, LMNA, MYC, NCOA4 |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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