| Gene Symbol | LRRK2PROTEIN |
| Function | is a large multi-domain protein encoded by the LRRK2 gene. |
| Subcellular Localization | </b></td><td>Cytoplasm, membranes, mitochondria</td></tr> |
| Molecular Weight | 286 kDa |
| Amino Acids | 2527 aa |
| GeneCards | LRRK2PROTEIN |
| Human Protein Atlas | LRRK2PROTEIN |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | BIIB094, BIIB122, Cigarette Smoking, DNL201, Environmental Toxicants, levodopa |
| Interactions | 6-OHDA, ACETYLCHOLINE, ACHE, Actin, AD, AKT |
| SciDEX Hypotheses | G2019S primarily raises baseline LRRK2 kinase acti Therapeutic Window Exists Because Amplified Signal LRRK2 Volume Sensor Hijacking Drives Metabolic Dys (+2 more) |
| KG Connections | 2616 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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