| Gene Symbol | JNK1 |
| Aliases | MAPK8 |
| Protein Type | Kinase |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </strong></td><td>Cytoplasm, nucleus (upon activation)</td></tr> |
| Molecular Weight | 46 kDa |
| Amino Acids | 464 aa |
| Exons | 12 |
| Pathways | cascade: **Upstream Activation:**, MAPK, Mapk |
| Ensembl ID | ENSG00000107643 |
| GeneCards | JNK1 |
| Human Protein Atlas | JNK1 |
| JNK1α1 | 46 kDa, widely expressed |
| JNK1α2 | 46 kDa, alternative C-terminus |
| JNK1β1/β2 | Extended isoforms with distinct tissue distribution |
| Associated Diseases | ALS |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACC, AMPK, AND, ASTROCYTES, ATG5, ATM |
| KG Connections | 166 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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