| Gene Symbol | IREB2 |
| Full Name | Iron Responsive Element Binding Protein 2 |
| Chromosome | 15q25.1 |
| Function | is a central pathogenic mechanism in neurodegeneration. |
| Primary Expression | Hippocampus, Substantia nigra, Cortex, Basal ganglia (enriched in brain) |
| Molecular Weight | 105 kDa |
| Amino Acids | 963 aa |
| Exons | 22 |
| Pathways | Apoptosis, Complement, Exocytosis, Mitochondrial Function |
| UniProt ID | P48200 |
| NCBI Gene ID | 3658 |
| Ensembl ID | ENSG00000136381 |
| OMIM | 147582 |
| GeneCards | IREB2 |
| Human Protein Atlas | IREB2 |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, NBIA, Neurodegeneration with brain iron accumulation |
| Interactions | ABCB1, ALOX12, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND |
| KG Connections | 88 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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