protein 821 words KG: HEXAPROTEIN
Contents

Hexosaminidase A (Hex A) Protein

🔬 Protein Info
Gene SymbolHEXAPROTEIN
Protein FamilyGlycoside hydrolase family 20
Protein TypeEnzyme
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight~110 kDa (heterodimer)
Amino Acids529 aa
UniProt IDP06865
GeneCardsHEXAPROTEIN
Human Protein AtlasHEXAPROTEIN
Associated Diseasesdisease
InteractionsDEMENTIA, GBA, NEURON, PARKINSON, PARKINSON'S DISEASE, Rb
KG Connections33 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (13)

Microglial Efferocytosis Enhancement via GPR32 Superagonists
Score: 0.70
Complement C1q Mimetic Decoy Therapy
Score: 0.69
Oligodendrocyte Protectin D1 Mimetic for Myelin Resolution
Score: 0.68
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Sphingolipid Metabolism Reprogramming
Score: 0.62
VCP-Mediated Autophagy Enhancement
Score: 0.59
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (8)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.