| Gene Symbol | GALC |
| Full Name | Galactocerebrosidase |
| Chromosome | 14q31.3 (Chr14: 87,934,475-88,013,430) |
| Function | GALC encodes galactocerebrosidase, a lysosomal hydrolase that catalyzes the hydrolysis of galactocerebroside, a major lipid component of myelin. |
| Primary Expression | brain white matter, peripheral nerves |
| Molecular Weight | 80 kDa |
| Pathways | Tgf-Β |
| UniProt ID | P54803 |
| NCBI Gene ID | 2581 |
| Ensembl ID | ENSG00000135837 |
| OMIM | 245000 |
| GeneCards | GALC |
| Human Protein Atlas | GALC |
| N-terminal signal peptide | Directs secretion and lysosomal targeting |
| Catalytic domain | TIM barrel fold (aa 200-540) containing the active site |
| Associated Diseases | Ms |
| Interactions | AUTOPHAGY, CANCER, CTSD, GLA, GPR37, LRRK2 |
| KG Connections | 41 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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