| Gene Symbol | FIS1 |
| Full Name | Fission 1 Mitochondrial Outer Membrane Protein |
| Aliases | FIS1PROTEIN |
| Chromosome | 7q22.1 |
| Protein Type | Mitochondrial outer membrane protein |
| Function | Fis1 Gene plays an important role in the study of neurodegenerative diseases |
| Molecular Weight | 17 kDa |
| Pathways | Apoptosis, Autophagy, Lysosomal Degradation, Mitochondrial Function, Mitophagy |
| GeneCards | FIS1 |
| Human Protein Atlas | FIS1 |
| Drp1 recruitment | Adaptor protein for Drp1 |
| Fission site selection | Marks fission competent sites |
| OMM constriction | Initiates membrane弯曲 |
| ERGIC interaction | Connected to ER-mitochondria contacts |
| Mitochondrial quality control | Enables mitophagy |
| Associated Diseases | Aging, Als, Cardiomyopathy, Inflammation, Lymphoma |
| Known Drugs/Compounds | RAPAMYCIN |
| Interactions | AGING, AMPK, AND, APP, ATP, AUTOPHAGY |
| KG Connections | 359 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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