| Gene Symbol | DRAM1 |
| Full Name | DNA Damage Regulated Autophagy Modulator 1 |
| Chromosome | 7q34 |
| Function | DRAM1 is a lysosomal membrane protein that acts as a key regulator of autophagy, a cellular process critical for clearing misfolded proteins and damaged organelles. |
| Subcellular Localization | the lysosome and endoplasmic reticulum. It functions as a key regulator of autophagy, particularly in response to cellul |
| Molecular Weight | 37 kDa |
| Pathways | mTOR, mtor |
| UniProt ID | DRAM1 |
| NCBI Gene ID | 55332 |
| Ensembl ID | ENSG00000138271 |
| OMIM | 610686 |
| GeneCards | DRAM1 |
| Human Protein Atlas | DRAM1 |
| N-terminus | Cytoplasmic domain (aa 1-50) |
| 6 Transmembrane Domains | α-helical |
| Associated Diseases | Lupus |
| Interactions | AMPK, AUTOPHAGY, SNAP29, STIM1, STX17, ULK1 |
| KG Connections | 39 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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