| Gene Symbol | DLK |
| Full Name | Dual Leucine Zipper Kinase |
| Aliases | MAP3K12 |
| Protein Type | Kinase |
| Function | DLK functions as a master regulator of the stress-activated protein kinase (SAPK) signaling cascade: |
| Molecular Weight | 105 kDa |
| Pathways | cascade: ### Axonal Injury Response |
| Ensembl ID | ENSG00000116809 |
| GeneCards | DLK |
| Human Protein Atlas | DLK |
| N-terminal regulatory region | Contains leucine zipper motifs for dimerization and protein interactions |
| C-terminal region | Multiple protein interaction motifs |
| Dimerization interface | Leucine zippers mediate homodimerization |
| Multiple phosphorylation sites | Regulatory control of kinase activity [1] |
| Activation loop | Phosphorylation sites for activation |
| Associated Diseases | Aging |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND, APOE, APOE3 |
| KG Connections | 106 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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