| Gene Symbol | DCCPROTEIN |
| Full Name | DCC Netrin 1 Receptor Protein |
| Protein Family | Ig superfamily, DCC family |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </td><td>Plasma membrane, cytoplasm</td></tr> |
| Molecular Weight | ~175 kDa |
| Amino Acids | 447 aa |
| UniProt ID | Q9Y266 |
| GeneCards | DCCPROTEIN |
| Human Protein Atlas | DCCPROTEIN |
| Transmembrane Domain | Single pass α-helical transmembrane region |
| Cytoplasmic Tail | Contains multiple signaling motifs: |
| With Netrin-1 | Activates pro-survival signaling (PI3K/AKT, MAPK/ERK pathways) |
| Without Netrin-1 | Induces apoptosis through caspase activation and mitochondrial pathways |
| Associated Diseases | Als, cancer |
| Interactions | AKT, APOPTOSIS, CANCER, CD44, EPHA4, FGF10 |
| KG Connections | 83 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!
No comments yet. Be the first to comment!