protein 645 words KG: CTCFPROTEIN
Contents

CTCF Protein

🔬 Protein Info
Gene SymbolCTCF
Full NameCCCTC-Binding Factor
Chromosome16q22.1
FunctionThe CTCF gene encodes CCCTC-Binding Factor, a highly conserved zinc finger transcription factor that is one of the most important architectural proteins in the mammalian genome.
Primary Expressionboth excitatory and inhibitory neurons throughout development and in adulthood
Subcellular Localization</strong></td><td>Nucleus (chromatin-bound)</td></tr>
Molecular Weight83 kDa
PathwaysAutophagy, Cell Cycle, Epigenetic, Inflammasome, Neurogenesis
UniProt IDP49711
NCBI Gene ID1065
Ensembl IDENSG00000102974
OMIM114167
GeneCardsCTCF
Human Protein AtlasCTCF
N-terminal domainContains activation and repression domains
Associated DiseasesCancer
InteractionsANXIETY, BDNF, BNIP3L, CANCER, DNA, E2F3
KG Connections78 knowledge graph edges
DatabasesGeneCardsHPASTRING

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