protein 752 words KG: CPLX3PROTEIN
Contents

Complexin-3 (CPLX3)

🔬 Protein Info
Gene SymbolCPLX3
Full NameComplexin-3
Chromosome5q23.1
Functionis a neuronal protein that regulates synaptic vesicle fusion by binding to the SNARE complex.
Primary Expressionphotoreceptor cells, bipolar cells, and various brain regions including the hippocampus and cortex
Subcellular Localization</b></td><td>Cytosol, Synaptic vesicles, Presynaptic terminal</td></tr>
Amino Acids156 aa
UniProt IDQ9BQY1
NCBI Gene ID81571
Ensembl IDENSG00000177468
OMIM618251
GeneCardsCPLX3
Human Protein AtlasCPLX3
N-terminal domainInvolved in SNARE complex binding and fusion regulation
Central helical domainForms parallel coiled-coil structure that bridges SNARE complexes
Associated Diseasesvision
InteractionsAND, GBM, GENES, HCRTR1, Igf
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

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