protein 618 words KG: BAG3PROTEIN
Contents

BAG3 Protein

🔬 Protein Info
Gene SymbolBAG3
Full NameBCL2 Associated Athanogene 3
AliasesBAG3PROTEIN
Chromosome10q25.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight57.5 kDa
Amino Acids575 aa
Exons4
PathwaysAutophagy, Complement, Nf-Κb
GeneCardsBAG3
Human Protein AtlasBAG3
Associated DiseasesAls, Alzheimer's disease, ALZHEIMERS_DISEASE, Amyotrophic Lateral Sclerosis, Astrocyte Phagocytosis
Known Drugs/Compoundsrapamycin
InteractionsALPHA_SYNUCLEIN, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid-Beta, AMYLOID-BETA
KG Connections416 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (7)

Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 3 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 3 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

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