| Gene Symbol | AURKBPROTEIN |
| Chromosome | 17p13.1 |
| Protein Type | Serine/Threonine Kinase |
| Function | is a chromosomal passenger protein and serine/threonine kinase that plays critical roles in mitosis, cytokinesis, and regulation of histone modifications. |
| Primary Expression | post-mitotic neurons where it performs distinct functions |
| Subcellular Localization | ** | Centromere, midbody, nucleus | |
| Molecular Weight | 39 kDa |
| GeneCards | AURKBPROTEIN |
| Human Protein Atlas | AURKBPROTEIN |
| Histone H3 | Serine 10 phosphorylation promotes chromatin condensation |
| INCENP | Autophosphorylation enhances CPC activity |
| MgcRacGAP | Regulation of Rho GTPases during cytokinesis |
| Kinetochore proteins | MLKN1, CENP-A, borealin for proper kinetochore function |
| Synaptic vesicle trafficking | Regulates presynaptic vesicle dynamics |
| Dendritic spine morphology | Controls spine formation and maintenance |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACTB, AMPK, ASPM, ATG, CALM1, CANCER |
| KG Connections | 85 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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