gene 3,060 words KG: PARK7
Contents

PARK7 — Parkinsonism Associated Deglycase (DJ-1)

🧬 Gene Info
Gene SymbolPARK7
Full NameParkinsonism Associated Deglycase (DJ-1)
AliasesPage for PARK7 Gene
Chromosome1p36.23
Protein TypeProtein
FunctionDJ-1 has multiple cellular functions
Primary ExpressionHigh in brain (substantia nigra), testis, kidney
Subcellular LocalizationCytoplasm, nucleus, mitochondria
Molecular Weight20 kDa
Amino Acids189 aa
PathwaysAlpha-Synuclein, Autophagy, Epigenetic, Er Stress, Inflammasome
UniProt IDQ99497
GeneCardsPARK7
Human Protein AtlasPARK7
Associated DiseasesAD, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
InteractionsACETYL-COA, AD, AGING, AKT, Alpha-Synuclein, ALS
KG Connections608 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

PARK7 associated_with neurodegeneration
PARK7 regulates SOD1
SOD1 regulates PARK7
PARK7 associated_with SOD1
PARK7 associated_with TAU
LRRK2 associated_with PARK7
PARK7 co_discussed SOD1
PARK7 co_discussed TAU
LRRK2 co_discussed PARK7
PARK7 co_discussed PINK1

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