gene 584 words KG: NMNAT2
Contents

NMNAT2 Gene

🧬 Gene Info
Gene SymbolNMNAT2
Full NameNMN Adenylyltransferase 2
Chromosome1p36.22
Protein TypeEnzyme
FunctionNMNAT2 is a cytosolic enzyme that catalyzes the conversion of NMN (nicotinamide mononucleotide) to NAD+ (nicotinamide adenine dinucleotide).
Subcellular Localization**: Cytosolic, enriched in axons
Molecular Weight46.2 kDa
PathwaysComplement, Immune Response, Mapk
UniProt IDQ9H0M0
NCBI Gene ID23257
Ensembl IDENSG00000145425
OMIM608401
GeneCardsNMNAT2
Human Protein AtlasNMNAT2
Associated Diseasesneurodegeneration
InteractionsAND, AXON, C4B, COMPLEMENT, MAPK, NEURODEGENERATIVE DISEASES
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (1)

SARM1-Mediated NAD+ Depletion as Terminal Executor of MCT1-D
Score: 0.70

Knowledge Graph (12 edges)

NMNAT2 activates C4B
NMNAT2 activates NRP1
MAPK activates NMNAT2
SARM1 activates NMNAT2
AXON protects_against NMNAT2
AND activates NMNAT2
NEURODEGENERATIVE DISEASES activates NMNAT2
NMNAT2 activates Ms
NMNAT2 activates Als
NMNAT2 activates Mapk

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)