| Gene Symbol | LRRK2 |
| Full Name | 14-3-3 Interaction Network |
| Chromosome | 12q12 |
| Protein Type | Protein |
| Subcellular Localization | , kinase activity, and pathogenic signaling in Parkinson's disease (PD). The 14-3-3 prot |
| Amino Acids | 2527 aa |
| Pathways | MAPK |
| UniProt ID | Search UniProt |
| GeneCards | LRRK2 |
| Human Protein Atlas | LRRK2 |
| Armadillo repeats (12-330) | Protein-protein interactions |
| Ankyrin repeats (331-500) | Additional interaction surfaces |
| Associated Diseases | Aging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | BIIB094, Cigarette Smoking, Environmental Toxicants, levodopa, LPS, LRRK2 inhibitors |
| Interactions | 6-OHDA, ACETYLCHOLINE, ACHE, Actin, AD, AKT |
| SciDEX Hypotheses | G2019S primarily raises baseline LRRK2 kinase acti |
| KG Connections | 2611 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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