| Gene Symbol | ZNF7 |
| Full Name | Zinc Finger Protein 7 |
| Chromosome | 8q24.21 |
| Protein Type | Transcription Factor |
| Function | ZNF7 (Zinc Finger Protein 7), also known as ZNF45 or KOX15, is a C2H2-type zinc finger transcription factor that belongs to the Krüppel-associated box (KRAB) family [1] |
| Amino Acids | 650 aa |
| Pathways | Inflammasome, Innate Immunity |
| Ensembl ID | ENSG00000124783 |
| GeneCards | ZNF7 |
| Human Protein Atlas | ZNF7 |
| KRAB domain | Located at the N-terminus (approximately 100 amino acids), consisting of two subdomains (A and B) that mediate transcriptional repression |
| Zinc finger domain | Contains 15 C2H2-type zinc fingers at the C-terminus, each approximately 30 amino acids in length |
| Nuclear localization signals | Present within the zinc finger region |
| Associated Diseases | neurodegeneration |
| Interactions | INFLAMMATION, UBIQUITIN |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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