gene 1,067 words KG: TERC
Contents

TERC Gene

🧬 Gene Info
Gene SymbolTERC
Full NameTelomerase RNA Component
Chromosome3q26.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids~451 nucleotides
PathwaysTelomere Dysfunction
NCBI Gene ID7012
Ensembl IDENSG00000264364
OMIM602322
GeneCardsTERC
Human Protein AtlasTERC
Associated DiseasesAls, Inflammation, Ms, Senescence
InteractionsIL-6, IL-8, MICRORNAS
KG Connections61 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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Knowledge Graph

Related Hypotheses (30)

LRP1-Dependent Tau Uptake Disruption
Score: 0.58
Synaptic Vesicle Tau Capture Inhibition
Score: 0.55
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88

Related Analyses (28)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (4)

Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: contributes_to
Genes
index · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: contributes_to

Knowledge Graph (12 edges)

TERT associated_with TERC
TERT expressed_in TERC
TERC involved_in Telomere Dysfunction
TERC regulates Telomere Dysfunction
TERC involved_in Telomere Maintenance
TERT encodes TERC
TERC causes Telomere Dysfunction
TERC regulates Senescence
TERC associated_with Als
TERC regulates Ms

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