| Gene Symbol | STX3 |
| Full Name | Syntaxin 3 |
| Aliases | Syntaxin 3 gene encoding a SNARE protein critical for synaptic vesicle exocytosis and membrane fusion in neurons |
| Chromosome | 11q12.1 |
| Function | Vesicle docking: STX3 localizes to the plasma membrane at the active zone and interacts with vesicle-associated VAMP2 |
| Primary Expression | astrocytes where it regulates[@tomm2019]: |
| Amino Acids | 289 aa |
| Pathways | Autophagy |
| UniProt ID | [Q99986](https://www.uniprot.org/uniprot/Q99986) |
| Ensembl ID | ENSG00000166900 |
| OMIM | 600078 |
| GeneCards | STX3 |
| Human Protein Atlas | STX3 |
| STX3 | Target membrane Q-SNARE |
| SNAP25 | Synaptosome-associated protein (two SNARE motifs) |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| KG Connections | 22 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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