| Gene Symbol | SRRM2 |
| Full Name | Serine/Arginine Repetitive Matrix 2 |
| Chromosome | 19q13.2 |
| Function | The SRRM2 gene encodes a protein involved in RNA processing and splicing mechanisms critical for neuronal function and survival. |
| Primary Expression | various brain regions, including the cortex, hippocampus, and spinal cord, where it supports pr |
| Subcellular Localization | nuclear speckles, subnuclear domains enriched in splicing factors and nascent pre-mRNA transcripts. SRRM2 has emerged as |
| Pathways | Nuclear Speckle Integrity |
| UniProt ID | Q9Y5Y9 |
| Ensembl ID | ENSG00000167981 |
| GeneCards | SRRM2 |
| Human Protein Atlas | SRRM2 |
| SRSF1, SRSF2 | other SR splicing factors interacting with SRRM2 |
| Spliceosome | molecular machine SRRM2 regulates |
| FUS, TARDBP | alternative |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, Dementia, frontotemporal dementia, Ftd |
| Interactions | Poly-GR Protein, TDP-43 |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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