gene 2,374 words KG: RPS10
Contents

RPS10 Gene - Ribosomal Protein S10

🧬 Gene Info
Gene SymbolRPS10
Functionis a highly conserved ribosomal protein that participates in multiple aspects of ribosome function.
Molecular Weight18.9 kDa
Amino Acids165 aa
Ensembl IDENSG00000124614
GeneCardsRPS10
Human Protein AtlasRPS10
N-terminal regionInvolved in rRNA binding
C-terminal domainMediates interactions with other ribosomal proteins
Surface residuesForm binding sites for translation factors
InheritanceAutosomal dominant (most cases)
Mutation typesMissense, nonsense, frameshift
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsRPL35, RPL38, RPS16, RPS27, RPS28, TARDBP
KG Connections7 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (13)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
APOE-Dependent Autophagy Restoration
Score: 0.85
Senescence-Activated NAD+ Depletion Rescue
Score: 0.76
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73

Related Analyses (7)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (7)

Neurodegeneration
disease · KG edge: implicated_in
RPL35 Gene
gene · KG edge: interacts_with
RPL38 Gene - Ribosomal Protein L38
gene · KG edge: interacts_with
RPS16 — Ribosomal Protein S16
gene · KG edge: interacts_with
rps27
gene · KG edge: interacts_with

Knowledge Graph (7 edges)

RPS28 interacts_with RPS10
RPL35 interacts_with RPS10
TARDBP interacts_with RPS10
RPS10 interacts_with RPS16
RPS10 interacts_with RPS27
RPS10 interacts_with RPL38
RPS10 regulates Ms

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