| Gene Symbol | PSMC1 |
| Full Name | Proteasome 26S Subunit, ATPase 1 |
| Aliases | Proteasome 26S Subunit ATPase 1 |
| Chromosome | 19q13.33 |
| Protein Type | Protease |
| Function | PSMC1 (Proteasome 26S Subunit, ATPase 1) encodes a member of the ATPase family that functions as a regulatory subunit of the 26S proteasome. |
| Primary Expression | all tissues, with high expression in brain, particularly in neurons of the cerebral cortex, [hippocampus](/brain-regions/hipp |
| Subcellular Localization | both cytosolic and nuclear compartments, consistent with its role in cytosolic and nuclear protein degradation [7](https |
| Pathways | Autophagy, Proteasome |
| UniProt ID | PSMC1 |
| Ensembl ID | ENSG00000121039 |
| GeneCards | PSMC1 |
| Human Protein Atlas | PSMC1 |
| Associated Diseases | neurodegeneration |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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