| Gene Symbol | PCBP2 |
| Full Name | Poly(rC) Binding Protein 2 |
| Chromosome | 12q13.13 |
| Function | Different KH domain combinations confer substrate specificity and tissue-specific functions. |
| Primary Expression | most neuronal subtypes with particular enrichment in glutamatergic neurons |
| Molecular Weight | 38 kDa |
| Amino Acids | 361 aa |
| UniProt ID | Q15366 |
| NCBI Gene ID | 5096 |
| Ensembl ID | ENSG00000197111 |
| GeneCards | PCBP2 |
| Human Protein Atlas | PCBP2 |
| mRNA stability | PCBP2 binds to AU-rich elements (AREs) and C-rich sequences in mRNA 3'UTRs, regulating mRNA decay rates |
| Translation regulation | PCBP2 can either promote or inhibit translation depending on context and bound sequence |
| Alternative splicing | PCBP2 influences splice site selection in pre-mRNA processing |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | CN-0928 |
| Interactions | ATG5, FTH1, LC3 |
| KG Connections | 21 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!