gene 700 words KG: MTERF1
Contents

MTERF1 Gene - Mitochondrial Transcription Termination Factor 1

🧬 Gene Info
Gene SymbolMTERF1
Full NameMitochondrial Transcription Termination Factor 1
AliasesPage for MTERF1 Gene
Chromosome7q21.3
FunctionMTERF1 is a mitochondrial protein that regulates transcription of mitochondrial DNA (mtDNA)
Primary ExpressionHigh in brain, heart, skeletal muscle (mitochondrial)
Amino Acids399 aa
Exons2
UniProt IDP56183
NCBI Gene ID5101
Ensembl IDENSG00000138442
OMIM605350
GeneCardsMTERF1
Human Protein AtlasMTERF1
Associated DiseasesParkinson's Disease, Alzheimer's Disease, Mitochondrial Disorders
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (15)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (11)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (4)

Neurodegeneration
disease · KG edge: implicated_in
REST Gene
gene · KG edge: regulates
TFAM Gene
gene · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: regulates

Knowledge Graph (6 edges)

REST regulates MTERF1
TFAM regulates MTERF1
MTDNA regulates MTERF1
MITOCHONDRIAL DNA regulates MTERF1
MTERF1 regulates Als
MTERF1 regulates Ms

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.