| Gene Symbol | KMT2C |
| Full Name | Lysine Methyltransferase 2C |
| Protein Type | Transferase |
| Function | KMT2C (also known as MLL3) is a histone H3K4 monomethyltransferase that plays a critical role in transcriptional activation through chromatin remodeling. |
| Primary Expression | all regions - Cerebellum: Present in granule cells - Allen Brain Atlas: [KMT2C expression data](https://human |
| Amino Acids | 900 aa |
| Ensembl ID | ENSG00000055607 |
| GeneCards | KMT2C |
| Human Protein Atlas | KMT2C |
| H3K4 Methylation | Catalyzes H3K4me1, a mark associated with enhancer activation |
| Transcriptional Coactivation | Works with the COMPASS complex |
| Metabolic Regulation | Involved in adipogenesis and lipid metabolism |
| SET Domain | Catalytic methyltransferase domain |
| PHD Fingers | Zinc fingers for chromatin reader function |
| FYR Domain | Fungal yeast R-related domains |
| Associated Diseases | neurodegeneration |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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