Contents

IL17A — Interleukin 17A

🧬 Gene Info

Gene Symbol	IL17A
Full Name	Interleukin 17A
Chromosome	6p12.2.
Function	is a 155-amino acid secreted glycoprotein that forms disulfide-linked homodimers.
Primary Expression	non-immune cells including neurons and glia
Amino Acids	155 aa
Pathways	NF-κB pathway, MAPK pathway, TGF-β
UniProt ID	[Q16552](https://www.uniprot.org/uniprot/Q16552)
Ensembl ID	ENSG00000112116
OMIM	603250
GeneCards	IL17A
Human Protein Atlas	IL17A
IL17RC	co-receptor, especially highly expressed in non-immune cells including neurons and glia
NF-κB pathway	Classical pro-inflammatory signaling via IKK complex activation
MAPK pathways	C/EBPβ, C/EBPδ, and AP-1 family transcription factors
Associated Diseases	Senescence
Known Drugs/Compounds	hyperforin
Interactions	BMAL1, DNMT1, PARKIN, TNF
KG Connections	20 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

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