gene 695 words KG: GSK3A
Contents

GSK3A Gene

🧬 Gene Info
Gene SymbolGSK3A
Full NameGlycogen Synthase Kinase 3 Alpha
Chromosome19q13.2
Protein TypeKinase
FunctionGSK3A encodes a serine/threonine-protein kinase that is constitutively active in neurons.
Molecular Weight52.9 kDa
PathwaysNF-κB, Wnt, PI3K, MAPK
UniProt IDGSK3A
NCBI Gene ID2931
Ensembl IDENSG00000105723
OMIM604489
GeneCardsGSK3A
Human Protein AtlasGSK3A
Associated Diseasesneurodegeneration
InteractionsALZHEIMER, ALZHEIMER'S DISEASE, APOPTOSIS, APP, APP/PS1, MICROGLIA
KG Connections27 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Microglia
cell · KG edge: activates
Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: activates
Microglia in Neurodegeneration
entity · KG edge: activates
Neurogenesis
entity · KG edge: activates

Knowledge Graph (12 edges)

SIRT3 activates GSK3A
GSK3A activates APP
GSK3A activates SIRT3
GSK3A expressed_in Neural Stem Cell
GSK3A associated_with GSK3B
MICROGLIA activates GSK3A
ALZHEIMER'S DISEASE activates GSK3A
GSK3A activates APP/PS1
GSK3A activates MITOCHONDRIAL DYSFUNCTION
GSK3A activates APOPTOSIS

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