gene 525 words KG: DR3
Contents

DRD3 — Dopamine Receptor D3

🧬 Gene Info
Gene SymbolDRD3
Full NameDopamine Receptor D3
Chromosome3q13.31
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe limbic system and plays critical roles in reward, motivation, and movement control
Molecular Weight130 kDa
PathwaysMAPK, PI3K
UniProt IDP35462
NCBI Gene ID1818
Ensembl IDENSG00000151577
OMIM139251
GeneCardsDRD3
Human Protein AtlasDRD3
Gα signalingCoupling to Gα subunits leads to modulation of adenylyl cyclase and phospholipase C
Associated Diseasesneurodegeneration
Known Drugs/CompoundsD-520
InteractionsAMPK, DRD2, ULK1
KG Connections10 knowledge graph edges
DatabasesGeneCardsHPASTRING

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