| Gene Symbol | DNAJA2 |
| Protein Type | Chaperone |
| Function | DNAJA2 (DnaJ Heat Shock Protein Family (Hsp40) Member A2) is a co-chaperone that stimulates the ATPase activity of Hsp70 proteins. |
| Primary Expression | various cancers |
| Ensembl ID | ENSG00000067715 |
| GeneCards | DNAJA2 |
| Human Protein Atlas | DNAJA2 |
| J-domain protein (JDP) | Contains characteristic J-domain that activates Hsp70 ATPase |
| Substrate delivery | Binds misfolded proteins and delivers them to Hsp70 |
| Protein folding | Assists Hsp70 in de novo protein folding |
| Protein refolding | Helps refold stress-denatured proteins |
| Protein degradation | Targets misfolded proteins for proteasomal or autophagic clearance |
| Transcription regulation | Associates with transcription factors |
| Associated Diseases | neurodegeneration |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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