| Gene Symbol | CTSK |
| Full Name | Cathepsin K |
| Chromosome | 1q21.3 |
| Protein Type | Protease |
| Function | is a gene encoding a member of the papain family of cysteine proteases with remarkable collagenolytic activity. |
| Primary Expression | various tissues including the brain, where it participates in extracellular matrix remodeling, protein aggregate clearance, and neuroinflammatory proc |
| Amino Acids | 329 aa |
| UniProt ID | [P43235](https://www.uniprot.org/uniprot/P43235) |
| Ensembl ID | ENSG00000136754 |
| OMIM | 601105 |
| GeneCards | CTSK |
| Human Protein Atlas | CTSK |
| Propeptide | 15-20 residues that maintain enzyme latency |
| Catalytic domain | ~215 residues containing the active site |
| Unique N-terminal region | Conferring collagen-binding properties |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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