| Gene Symbol | ATG2B |
| Full Name | Autophagy Related 2B |
| Chromosome | 14q32.12 |
| Protein Type | Peripheral Membrane Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 223 kDa |
| Pathways | PI3K |
| UniProt ID | [Q9P2R3](https://www.uniprot.org/uniprot/Q9P2R3) |
| GeneCards | ATG2B |
| Human Protein Atlas | ATG2B |
| Overlapping functions | Both proteins participate in autophagosome expansion and lipid transfer |
| Compensatory expression | ATG2B can compensate for ATG2A loss in many cell types |
| Tissue specificity | ATG2B expression is enriched in certain tissues, particularly hematopoietic cells |
| Knockout studies | Single knockouts of either gene are viable; double knockout is embryonic lethal |
| Membrane expansion | Facilitates lipid delivery to growing autophagosomes |
| Associated Diseases | neurodegeneration |
| Interactions | ACETYL-COA, ATG5, AUTOPHAGY, CANCER, SIRT1 |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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