clinical 1,594 words KG: PD
Contents

NCT06487975: Bacillus Subtilis Gut Microbiome Intervention for PD

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Knowledge Graph

Agent Input

Related Hypotheses (8)

PARP1 Inhibition Therapy
Score: 0.74
Arginine Methylation Enhancement Therapy
Score: 0.65
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Optogenetic Control of Mitochondrial Transfer Networks
Score: 0.48
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43

Related Analyses (3)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
SCFA-Mediated Neuroinflammation in Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (11)

GBA1 (Redirect)
redirect · KG edge: causes
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: implicated_in
ABCB1 (MDR1) - ATP Binding Cassette Subfamily B Member
gene · KG edge: implicated_in
APOB Gene
gene · KG edge: implicated_in
CNTNAP4 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PD causes NEURODEGENERATION
PD causes DOPAMINERGIC_NEURONS
PD causes neurodegeneration
NEUROTROPHINS treats PD
AGE associated_with PD
SNCA causes PD
LRRK2 causes PD
GBA1 causes PD
PRKN causes PD
PINK1 causes PD

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