concept

CIRCFRMD4A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CIRCFRMD4A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections

0Hypotheses

0Analyses

11Outgoing

6Incoming

0Experiments

0Debates

No summary available yet.

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💡 Concept Info

Name	CIRCFRMD4A

Pathway Diagram

graph TD
    CIRCFRMD4A["CIRCFRMD4A"]
    CIRCFRMD4A -->|"suppresses"| Cancer["Cancer"]
    CIRCFRMD4A -->|"promotes"| Cuproptosis["Cuproptosis"]
    CIRCFRMD4A -->|"interacts"| PKM2["PKM2"]
    CIRCFRMD4A -->|"modulates"| Glycolytic_Metabolism["Glycolytic Metabolism"]
    CIRCFRMD4A -->|"mediates"| Glycolytic_Reprogramming["Glycolytic Reprogramming"]
    CIRCFRMD4A -->|"inhibits"| Cancer_Development["Cancer Development"]
    p53["p53"] -->|"activates"| CIRCFRMD4A
    TP53["TP53"] -->|"upregulates"| CIRCFRMD4A
    FRMD4A["FRMD4A"] -->|"expressed in"| CIRCFRMD4A
    EWSR1["EWSR1"] -->|"promotes"| CIRCFRMD4A

Outgoing (11)

Target	Relation	Type	Str
Glycolytic Metabolism	modulates	pathway	0.95
Cancer	suppresses	disease	0.95
PKM2	interacts_with	protein	0.95
PKM2	inhibits	protein	0.95
Cuproptosis	promotes	process	0.95
Cuproptosis	involved_in	process	0.94
Glycolytic Reprogramming	mediates	process	0.93
Cancer Development	inhibits	disease	0.92
PKM2	inhibits	protein	0.92
Elesclomol	associated_with	drug	0.90
PKM2	interacts_with	protein	0.90

Incoming (6)

Source	Relation	Type	Str
TP53	upregulates	gene	0.95
p53	activates	protein	0.95
FRMD4A	expressed_in	gene	0.90
EWSR1	promotes	gene	0.90
EWSR1	associated_with	protein	0.88
P53	regulates	gene	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CIRCFRMD4A in their description or question text

No additional research found