gene 1,505 words KG: ent-gene-ed5fed2c
Contents

ATG13 — Autophagy Related 13

🧬 Gene Info
Gene SymbolATG13
Full NameAutophagy Related 13
Chromosome11p11.2
Functionis a critical gene encoding a key regulator of the autophagy initiation machinery in eukaryotic cells.
Molecular Weight60 kDa
Amino Acids559 aa
PathwaysApoptosis, Autophagy, Complement, Ferroptosis, Glycolysis
UniProt ID[Q9UQL6](https://www.uniprot.org/uniprot/Q9UQL6)
Ensembl IDENSG00000152256
OMIM614608
GeneCardsATG13
Human Protein AtlasATG13
Hor domain (HR)Located at the N-terminus, mediates protein-protein interactions
LIR (LC3-interacting region)At the C-terminus, enables binding to LC3/GABARAP family proteins
UBAN-like motifFacilitates interaction with specific autophagy receptors
Associated Diseasesneurodegeneration
InteractionsAGING, ALS, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AMYLOID
KG Connections186 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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