| Gene Symbol | ADRA2B |
| Full Name | Alpha-2B Adrenergic Receptor |
| Chromosome | 2q24.1 |
| Protein Family | Adrenergic receptor family (GPCR) |
| Primary Expression | both the central and peripheral nervous systems, where it regulates norepinephrine release, blood pressure, and various autonomic functions |
| Molecular Weight | 60 kDa |
| Amino Acids | 450 aa |
| Pathways | PI3-K, Wnt |
| UniProt ID | P17787 |
| NCBI Gene ID | 151 |
| Ensembl ID | ENSG00000159692 |
| GeneCards | ADRA2B |
| Human Protein Atlas | ADRA2B |
| Gi/o Protein Coupling | Inhibits adenylate cyclase |
| Reduced cAMP | Decreased PKA activity |
| Associated Diseases | neurodegeneration |
| Interactions | ADRA2A, ASTROCYTE, Cytokine, CYTOKINES, ERK1/2, GENES |
| KG Connections | 76 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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