protein

YBX1-PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about YBX1-PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

YBX1 Protein

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🔬 Protein Info

Gene Symbol	YBX1
Full Name	PROTEIN
Chromosome	1p34.2
Function	is a multifunctional DNA- and RNA-binding protein that plays critical roles in transcriptional regulation, mRNA splicing, translation, and stress response.
Primary Expression	the CNS: - High expression in neurons throughout the brain - Present in astrocytes and [microglia](/c
Molecular Weight	36 kDa
Amino Acids	70 aa
Pathways	Glycolysis, Multidrug Resistance, Nf-Κb, Wnt, mRNA Stability
UniProt ID	P62962
NCBI Gene ID	5102
Ensembl ID	ENSG00000165996
OMIM	113703
GeneCards	YBX1
Human Protein Atlas	YBX1
Associated Diseases	Cancer
Known Drugs/Compounds	m5C, m5C-modified mRNAs, SU056
Interactions	ABCB1, AGO2, AKT, ALYREF, AND, App
KG Connections	148 knowledge graph edges
Databases	GeneCards HPA STRING

🧬 3D Structure Comparison — YBX1-PROTEIN Experimental (PDB) vs Predicted (AlphaFold) — click to expand

📄 Experimental Structure

1L3L — X-ray / Cryo-EM

🔮 AI Predicted Structure

P62962 — AlphaFold

Left: Experimental structure from RCSB PDB | Right: AI-predicted structure from AlphaFold | Powered by Mol*

Pathway Diagram

graph TD
    A["Gene expression"] --> B["YBX1 PROTEIN"]
    B --> C["Protein folding and
quality control"]
    B --> D["Cellular signaling"]
    C --> E["Proteostasis"]
    D --> F["Neurotoxicity"]
    E --> G["Disease outcome"]
    F --> G
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class B protein
    class G disease

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning YBX1-PROTEIN in their description or question text

No additional research found