Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about INSULIN SENSITIVITY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | INSULIN SENSITIVITY |
graph TD
INSULIN_SENSITIVITY[INSULIN SENSITIVITY]
Cis_Palmitoleic_Acid[Cis-Palmitoleic Acid] -->|upregulates| INSULIN_SENSITIVITY
Palmitoleic_Acid[Palmitoleic Acid] -->|upregulates| INSULIN_SENSITIVITY
metformin[metformin] -->|treats| INSULIN_SENSITIVITY
FGF21[FGF21] -->|regulates| INSULIN_SENSITIVITY
AKT[AKT] -->|increases| INSULIN_SENSITIVITY
SHBG[SHBG] -->|regulates| INSULIN_SENSITIVITY
PPARGC1A[PPARGC1A] -->|regulates| INSULIN_SENSITIVITY
AMPK[AMPK] -->|activates| INSULIN_SENSITIVITY| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Nmn | associated_with | compound | 0.95 |
| metformin | treats | drug | 0.90 |
| Palmitoleic Acid | upregulates | compound | 0.90 |
| IRISIN | associated_with | protein | 0.90 |
| Methionine Restriction | associated_with | process | 0.90 |
| Cis-Palmitoleic Acid | upregulates | compound | 0.90 |
| Cis-Palmitoleic Acid | associated_with | compound | 0.90 |
| FGF21 | regulates | protein | 0.85 |
| Crocetin | associated_with | compound | 0.85 |
| Cis-palmitoleic Acid | associated_with | chemical | 0.80 |
| AKT | increases | gene | 0.80 |
| SHBG | regulates | protein | 0.75 |
| PPARGC1A | regulates | gene | 0.70 |
| AMPK | activates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning INSULIN SENSITIVITY in their description or question text
No additional research found