Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CANCER CELL PROLIFERATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CANCER CELL PROLIFERATION |
| Related Pathways | JAK-STAT3 |
graph TD
CANCER_CELL_PROLIFERATION[CANCER CELL PROLIFERATION]
PRMT1[PRMT1] -->|activates| CANCER_CELL_PROLIFERATION
Glycolytic_Flux[Glycolytic Flux] -->|contributes to| CANCER_CELL_PROLIFERATION
Notch_Signaling_Pathway[Notch Signaling Pathway] -->|contributes to| CANCER_CELL_PROLIFERATION
JAK_STAT3[JAK-STAT3] -->|promotes| CANCER_CELL_PROLIFERATION
FLOT1[FLOT1] -->|modulates| CANCER_CELL_PROLIFERATION
KRAS[KRAS] -->|promotes| CANCER_CELL_PROLIFERATION
RAS_pathway[RAS pathway] -->|promotes| CANCER_CELL_PROLIFERATION
Integrin[Integrin] -->|activates| CANCER_CELL_PROLIFERATION
NCL[NCL] -->|drives| CANCER_CELL_PROLIFERATION| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Extracellular Matrix Stiffness | associated_with | mechanism | 0.95 |
| Glycolytic Flux | contributes_to | process | 0.90 |
| KRAS | promotes | gene | 0.90 |
| PRMT1 | activates | protein | 0.90 |
| Notch Signaling Pathway | contributes_to | pathway | 0.90 |
| FLOT1 | modulates | protein | 0.90 |
| Extracellular Matrix | associated_with | structure | 0.90 |
| PRMT1 | regulates | protein | 0.90 |
| JAK-STAT3 | promotes | pathway | 0.90 |
| RAS pathway | promotes | pathway | 0.85 |
| Integrin | activates | receptor | 0.85 |
| PD-L1 | involved_in | protein | 0.85 |
| NCL | drives | protein | 0.85 |
| CD274 | involved_in | protein | 0.85 |
| Polyphenols | inhibits | compound | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CANCER CELL PROLIFERATION in their description or question text
No additional research found