Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BEVACIZUMAB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | BEVACIZUMAB |
| Related Diseases | ANGIOGENESIS, AUTOPHAGY, CANCER, COLORECTAL CANCER, EPIGENETIC REGULATION |
graph TD
BEVACIZUMAB[BEVACIZUMAB]
BEVACIZUMAB -->|binds_to| VEGF[VEGF]
BEVACIZUMAB -->|treats| Metastatic_Colorectal_Cancer[Metastatic Colorectal Cancer]
BEVACIZUMAB -->|treats| colorectal_cancer[colorectal cancer]
BEVACIZUMAB -->|inhibits| Cardiac_Repair[Cardiac Repair]
BEVACIZUMAB -->|confers_resistance| AUTOPHAGY[AUTOPHAGY]
LACTATE[LACTATE] -->|activates| BEVACIZUMAB| Target | Relation | Type | Str |
|---|---|---|---|
| VEGF | binds_to | protein | 0.95 |
| Metastatic Colorectal Cancer | treats | disease | 0.95 |
| colorectal cancer | treats | disease | 0.93 |
| Cardiac Repair | inhibits | process | 0.80 |
| VEGF | inhibits | protein | 0.70 |
| AUTOPHAGY | associated_with | phenotype | 0.65 |
| AUTOPHAGY | activates | phenotype | 0.65 |
| CANCER | associated_with | disease | 0.45 |
| LACTATE | associated_with | phenotype | 0.45 |
| FIBROSIS | associated_with | disease | 0.45 |
| MACROPHAGE | associated_with | cell_type | 0.45 |
| COLORECTAL CANCER | associated_with | disease | 0.45 |
| EPIGENETIC REGULATION | associated_with | phenotype | 0.45 |
| INFLAMMATION | associated_with | phenotype | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LACTATE | activates | phenotype | 0.65 |
| COLORECTAL CANCER | associated_with | disease | 0.45 |
| ANGIOGENESIS | associated_with | phenotype | 0.45 |
| INFLAMMATION | associated_with | phenotype | 0.45 |
| AUTOPHAGY | associated_with | phenotype | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning BEVACIZUMAB in their description or question text
No additional research found