Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about UBQLN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | UBQLN1 |
| Full Name | Ubiquilin 1 |
| Chromosome | 9q21.33 |
| Function | is a gene located on chromosome 9q21. |
| Molecular Weight | 62.5 kDa |
| Amino Acids | 589 aa |
| Pathways | Autophagy |
| UniProt ID | [Q9UMX0](https://www.uniprot.org/uniprot/Q9UMX0) |
| Ensembl ID | ENSG00000135185 |
| GeneCards | UBQLN1 |
| Human Protein Atlas | UBQLN1 |
| Associated Diseases | neurodegeneration |
| Interactions | AUTOPHAGY |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
UBQLN1["UBQLN1"]
Atherosclerosis{"Atherosclerosis"}
UBQLN1 -->|"activates"| Atherosclerosis
Autophagy(["Autophagy"])
UBQLN1 -->|"activates"| Autophagy
CD36["CD36"]
UBQLN1 -->|"regulates"| CD36
AUTOPHAGY["AUTOPHAGY"]
UBQLN1 -->|"activates"| AUTOPHAGY
neurodegeneration["neurodegeneration"]
UBQLN1 -->|"implicated in"| neurodegeneration
CD36 -->|"regulates"| UBQLN1
style UBQLN1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Atherosclerosis | activates | disease | 0.65 |
| CD36 | regulates | gene | 0.60 |
| Autophagy | activates | pathway | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CD36 | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning UBQLN1 in their description or question text
No additional research found