concept

UBA52

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about UBA52: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

0Analyses

7Outgoing

7Incoming

0Experiments

0Debates

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💡 Concept Info

Name	UBA52
Key Genes/Proteins	AUTOPHAGY, MLKL, UBIQUITIN, USP7
Related Diseases	ALS

Pathway Diagram

graph TD
    UBA52["UBA52"]
    UBA52 -->|"involved_in"| Autophagy["Autophagy"]
    UBA52 -->|"stabilizes"| ALS["ALS"]
    UBA52 -->|"stabilizes"| MLKL["MLKL"]
    UBA52 -->|"stabilizes"| UBIQUITIN["UBIQUITIN"]
    UBA52 -->|"stabilizes"| AUTOPHAGY["AUTOPHAGY"]
    UBA52 -->|"stabilizes"| USP7["USP7"]
    MLKL -->|"interacts"| UBA52
    USP7 -->|"modifies"| UBA52
    AUTOPHAGY -->|"stabilizes"| UBA52
    UBIQUITIN -->|"stabilizes"| UBA52

Outgoing (7)

Target	Relation	Type	Str
Autophagy	involved_in	process	0.95
ALS	stabilizes	disease	0.65
Autophagy	stabilizes	pathway	0.60
MLKL	stabilizes	gene	0.60
UBIQUITIN	stabilizes	gene	0.60
AUTOPHAGY	stabilizes	gene	0.60
USP7	stabilizes	gene	0.60

Incoming (7)

Source	Relation	Type	Str
MLKL	interacts_with	gene	0.90
USP7	modifies	gene	0.90
USP7	interacts_with	protein	0.85
USP7	stabilizes	gene	0.60
MLKL	stabilizes	gene	0.60
AUTOPHAGY	stabilizes	gene	0.60
UBIQUITIN	stabilizes	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning UBA52 in their description or question text

No additional research found