protein

TUBB3PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TUBB3PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

TUBB3 (Tubulin Beta 3 Class III) is a neuron-specific microtubule protein that plays critical roles in neuronal development, axonal guidance, and maintenance of neuronal polarity.

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🔬 Protein Info

Gene Symbol	TUBB3PROTEIN
Target Class	Structural Protein
Function	is a neuron-specific microtubule protein that plays critical roles in neuronal development, axonal guidance, and maintenance of neuronal polarity.
Mechanism of Action	Small molecule stabilizers of microtubule structure or assembly
Druggability	Medium (0.49)
Clinical Stage	Approved
Molecular Weight	50 kDa
Amino Acids	450 aa
GeneCards	TUBB3PROTEIN
Human Protein Atlas	TUBB3PROTEIN
Associated Diseases	Alzheimer, Alzheimer's disease, Bone Metastasis, Huntington, Huntington's disease, neurodegeneration
Known Drugs/Compounds	rapamycin
Interactions	ACTB, Actin, ALZHEIMER, ALZHEIMER DISEASE, AND, APOPTOSIS
SciDEX Target	View Target Profile (8 clinical trials)
SciDEX Hypotheses	Quantum Coherence Disruption in Cellular Communica
KG Connections	414 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

tubb3-protein

protein · 1964 words

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Pathway Diagram

graph TD
    TUBB3PROTEIN["TUBB3PROTEIN"]
    neurodegeneration["neurodegeneration"]
    TUBB3PROTEIN -->|"implicated_in"| neurodegeneration
    style TUBB3PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning TUBB3PROTEIN in their description or question text

No additional research found