gene

trpv2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about trpv2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections

0Hypotheses

0Analyses

14Outgoing

3Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	TRPV2
Full Name	Transient Receptor Potential Cation Channel Subfamily V Member 2
Chromosome	17p11.2
Protein Family	TRPV (Vanilloid-like) family
Protein Type	Channel
Function	is a non-selective calcium channel belonging to the TRP (Transient Receptor Potential) superfamily of ion channels.
Primary Expression	the central and peripheral nervous systems, where it participates in various physiological and pathological processes
Molecular Weight	84 kDa
Amino Acids	761 aa
Exons	18
Pathways	NF-κB
UniProt ID	[Q9Y5S2](https://www.uniprot.org/uniprot/Q9Y5S2)
Ensembl ID	ENSG00000173372
OMIM	607949
GeneCards	TRPV2
Human Protein Atlas	TRPV2
Associated Diseases	neurodegeneration
Known Drugs/Compounds	Cannabigerol
Interactions	Akt, CAV1, CGAS, CX43, CXCL1, CXCL2
KG Connections	17 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

TRPV2 — Transient Receptor Potential Cation Channel Subfamily V Member 2

gene · 1737 words

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Pathway Diagram

graph TD
    TRPV2["TRPV2"]
    TRPV2 -.protects against.-> Cancer["Cancer"]
    TRPV2 -->|"activates"| Fibrosis["Fibrosis"]
    TRPV2 -.protects against.-> CANCER["CANCER"]
    TRPV2 -->|"activates"| CGAS["CGAS"]
    TRPV2 -->|"activates"| STING["STING"]
    TRPV2 -->|"activates"| DNA["DNA"]
    TRPV2 -.protects against.-> Er_Stress["Er Stress"]
    TRPV2 -->|"activates"| CX43["CX43"]
    Cannabigerol["Cannabigerol"] -->|"interacts"| TRPV2
    CXCL2["CXCL2"] -->|"activates"| TRPV2
    IL_1["IL-1"] -->|"activates"| TRPV2

Outgoing (14)

Target	Relation	Type	Str
Cancer	protects_against	disease	0.65
Fibrosis	activates	disease	0.65
CXCL1	activates	gene	0.60
CAV1	activates	gene	0.60
CANCER	protects_against	gene	0.60
DNA	activates	gene	0.60
Er Stress	protects_against	pathway	0.60
CX43	activates	gene	0.60
Nf-Κb	activates	pathway	0.60
Il-1	activates	protein	0.60
Akt	activates	protein	0.60
CGAS	activates	gene	0.60
Pi3K	activates	protein	0.60
STING	activates	gene	0.60

Incoming (3)

Source	Relation	Type	Str
Cannabigerol	interacts_with	compound	0.80
IL-1	activates	gene	0.60
CXCL2	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning trpv2 in their description or question text

No additional research found