protein

TET1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TET1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Tet1 Protein is involved in cellular processes relevant to neurodegeneration. For detailed information, refer to the References section.

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🔬 Protein Info

Gene Symbol	TET1PROTEIN
Full Name	Tet Methylcytosine Dioxygenase 1
Protein Family	TET family (2-oxoglutarate-dependent dioxygenases)
Protein Type	Protein
Function	is a 2-oxoglutarate-dependent dioxygenase that catalyzes the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC).
Primary Expression	embryonic stem cells and is essential for pluripotency
Subcellular Localization	Nucleus
Molecular Weight	235 kDa
UniProt ID	Search UniProt
GeneCards	TET1PROTEIN
Human Protein Atlas	TET1PROTEIN
Protein Name	Tet Methylcytosine Dioxygenase 1 Protein
Gene	TET1
PDB	6VN6, 6VN7
Associated Diseases	neurodegeneration
Known Drugs/Compounds	Arsenic
Interactions	BDNF, DNA, DNMT1, ERK, GENES, IFN
KG Connections	34 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: TET1PROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Tet Methylcytosine Dioxygenase 1 Protein

protein · 502 words

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Pathway Diagram

graph TD
    TET1PROTEIN["TET1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    TET1PROTEIN -->|"implicated_in"| neurodegeneration
    style TET1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TET1PROTEIN in their description or question text

No additional research found